The pathogenesis of tuberculous meningitis

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Pathogenesis and immune response in tuberculous meningitis.

Cerebral tuberculosis is the most severe type of extrapulmonary disease that is in developing countries highly predominant in children. Meningeal tuberculosis is the most common form and usually begins with respiratory infection followed by early haematogenous dissemination to extrapulmonary sites involving the brain. In comparison with the lung, Mycobacterium tuberculosis induces a very differ...

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Central nervous system tuberculosis is the most severe form of extrapulmonary tuberculosis disease. We aim to review the diagnostic and radiological features, pathogenesis, and biomarkers of tuberculous meningitis. We also aim to look at the latest development of research of the disease. The diagnosis of tuberculous (TB) meningitis is difficult because the disease presents with unspecific clini...

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The Sequelae of Tuberculous Meningitis.

The classical description of the three stages in the clinical course of tuberculous meningitis was written nearly 200 years ago by Robert Whytt, Professor of Medicine at Edinburgh University; and his conclusions that 'if this disease could be known early . . . it might sometimes be cured, but as it never discovers itself . . . till the action of the brain is disturbed . . . we have little to ho...

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ژورنال

عنوان ژورنال: Journal of Leukocyte Biology

سال: 2019

ISSN: 0741-5400,1938-3673

DOI: 10.1002/jlb.mr0318-102r